Cancer BiologybioRxivPreprint
Pharmacological inhibition of LSD1 triggers myeloid differentiation by targeting GSE1, a novel oncogene in AML
L. Nicosia, F. L. Boffo, E. Ceccacci…·T. Bonaldi
This study shows that LSD1 inhibitors induce AML cell differentiation by reducing GSE1, a novel oncogene, through transcriptional activation of immune response genes.
DOI 10.1101/2021.02.16.431315