Author

T. Chernova

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

M. MacFarlane· 2 shared A. Craxton· 1 shared A. Dawson· 1 shared A. E. Willis· 1 shared A. Nakas· 1 shared C. Rooney· 1 shared D. J. Murphy· 1 shared D. Lewis· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCell Biology

M. MacFarlane

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2 papers

Recent·Most cited

Metabolic reprogramming provides a novel approach to overcome resistance to BH3-mimetics in Malignant Pleural Mesothelioma

X.-M. Sun, G. J. Miles, A. Craxton, I. R. Powley, S. Galavotti, T. Chernova, A. Dawson, A. Nakas, A. E. Willis, K. Cain, M. MacFarlane

This study identifies metabolic reprogramming as a strategy to overcome resistance to BH3-mimetics in MPM by combining glycolytic inhibition with MCL-1 and BCL-2/BCL-XL targeting.

bioRxiv · Mar 31, 2023 · PreprintCell Biology

Asbestos accelerates disease onset in a genetic model of Malignant Pleural Mesothelioma

P. Farahmand, K. Gyuraszova, C. Rooney, X. L. Raffo-Iraolagoitia, E. Johnson, T. Chernova, T. Monteverde, K. Blyth, R. Duffin, L. M. Carlin, D. Lewis, J. Le Quesne, M. MacFarlane, D. J. Murphy

This study shows asbestos accelerates mesothelioma onset and increases tumor burden in a genetic mouse model, with increased macrophage infiltration, but macrophage suppression did not improve survival.

bioRxiv · Jun 16, 2020Cancer Biology