Author

X.-M. Sun

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell type annotation· 2 Research Focus:development & morphogenesis· 2 Approach:genetic perturbation / CRISPR· 2 Organism:human· 2 Assay:proteomics· 2 Organism:yeast· 2 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

A. Craxton· 2 shared D. Keifenheim· 2 shared M. MacFarlane· 2 shared N. Rhind· 2 shared S. Marguerat· 2 shared A. Dawson· 1 shared A. E. Willis· 1 shared A. Nakas· 1 shared

Activity by Year

2017-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersCell Biology

A. Craxton

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4 papers

Recent·Most cited

Metabolic reprogramming provides a novel approach to overcome resistance to BH3-mimetics in Malignant Pleural Mesothelioma

X.-M. Sun, G. J. Miles, A. Craxton, I. R. Powley, S. Galavotti, T. Chernova, A. Dawson, A. Nakas, A. E. Willis, K. Cain, M. MacFarlane

This study identifies metabolic reprogramming as a strategy to overcome resistance to BH3-mimetics in MPM by combining glycolytic inhibition with MCL-1 and BCL-2/BCL-XL targeting.

bioRxiv · Mar 31, 2023 · PreprintCell Biology

TAp73 regulates mitochondrial dynamics and multiciliated cell homeostasis through an OPA1 axis

N. Buckley, A. Craxton, X.-M. Sun, E. Panatta, L. Pinon, J. Llodra, N. Morone, I. Amelio, G. Melino, L. M. Martins, M. MacFarlane

This study identifies TAp73's role in regulating mitochondrial dynamics and multiciliated cell homeostasis through the OPA1 axis, linking it to COPD pathogenesis.

bioRxiv · Mar 23, 2023Cell Biology

Post-Transcriptional Size-Dependent Expression of the Fission Yeast Cdc13 Cyclin

S. Bashir, X.-M. Sun, Y. Zhao, N. G. Martinez-Illescas, I. Gallego-Lopez, L. Guerrero Negron, D. Keifenheim, T. Karadimitriou, M. Pickering, S. Marguerat, N. Rhind

This study shows that Cdc13 in fission yeast is size-dependent at the protein level but not at the mRNA level, and identifies a motif responsible for this regulation, demonstrating it is not essential for size control.

bioRxiv · Jan 16, 2023 · PreprintCell Biology

Size-Dependent Accumulation of the Mitotic Activator Cdc25 as a Mechanism of Size Control in Fission Yeast

D. Keifenheim, X.-M. Sun, E. D'Souza, M. J. Ohira, M. Magner, M. B. Mayhew, S. Marguerat, N. Rhind

This study identifies a size-dependent Cdc25 expression mechanism in fission yeast that regulates cell size by controlling mitotic entry.

bioRxiv · Feb 28, 2017Cell Biology