Author

T. E. O'Sullivan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Organism:human· 2 Approach:statistical model· 2 Assay:ATAC-seq· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

L. Riggan· 2 shared A. P. Arnold· 1 shared C. Huerta· 1 shared E. Perez Reyes· 1 shared F. Ma· 1 shared H. Hrncir· 1 shared J. H. Li· 1 shared M. A. Su· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersImmunology

L. Riggan

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2 papers

Recent·Most cited

ImmunologybioRxivPreprintApr 21, 2022

Sex differences in NK cells mediated by the X-linked epigenetic regulator UTX

M. I. Cheng, L. Riggan, J. H. Li…·M. A. Su

This study identifies UTX as a key X-linked epigenetic regulator causing sex differences in NK cell function, with males showing reduced IFN-γ production despite higher numbers.

DOI 10.1101/2022.04.21.489076

mousehuman

𝕏 PostBluesky

ImmunologybioRxivPreprintNov 23, 2020

NK cells promote cancer immunoediting through tumor-intrinsic loss of interferon-stimulated gene expression

Y. Y. Wong, L. Riggan, C. Huerta…·T. E. O'Sullivan

This study shows that NK cell-edited tumors lose IFN-γ-inducible gene expression, and high expression of three genes correlates with better patient survival in breast, melanoma, and sarcoma.

DOI 10.1101/2020.11.23.394353

humanbulk RNA-seq

𝕏 PostBluesky