BiophysicsNaturePeer-reviewed
Structural basis of DNA targeting by a transposon-encoded CRISPR-Cas system
T. Halpin-Healy, S. Klompe, S. Sternberg, I. Fernandez
The paper determines the structure of a TniQ-Cascade complex using cryo-EM, revealing how it targets DNA and facilitates transposition by bacterial transposons.
DOI 10.1038/s41586-019-1849-0