Author

T. Huser

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 9 Cell Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Assay:fluorescence / live-cell microscopy· 7 Approach:microscopy & imaging analysis· 5 Research Focus:cell type annotation· 4 Approach:experimental assay· 4 Assay:imaging· 4 Organism:human· 3 Research Focus:imputation· 3 Assay:bulk RNA-seq· 1

Frequent Co-Authors

A. Sandmeyer· 4 shared M. Müller· 4 shared A. K. Engdahl· 3 shared W. Hübner· 3 shared H. Ortkrass· 2 shared H. Sandmeyer· 2 shared J. Schuerstedt· 2 shared K. Szafranska· 2 shared

Activity by Year

2019-2024 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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4 shared papersBiophysics

A. Sandmeyer

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Author profile →

11 papers

Recent·Most cited

High sensitivity cameras can lower spatial resolution in high-resolution optical microscopy

H. Ortkrass, M. Mueller, A. K. Engdahl, G. Holst, T. Huser

This study shows that highly sensitive cameras can reduce spatial resolution in high-resolution optical microscopy due to differences in their modulation transfer function.

bioRxiv · Feb 23, 2024Biophysics

High-speed TIRF and 2D super-resolution structured illumination microscopy with large field of view based on fiber optic components

H. Ortkrass, J. Schuerstedt, G. Wiebusch, K. Szafranska, P. McCourt, T. Huser

This paper presents a compact, high-speed SR-SIM system with large field of view and high spatiotemporal resolution for imaging rat liver sinusoidal endothelial cells.

bioRxiv · May 11, 2023Biophysics

Dual-color single molecule localization microscopy on transparent polymer waveguide chips

A. K. Engdahl, S. B. Dutta, S. Belle, J. Schuerstedt, K. Szafranska, R. Hellmann, P. McCourt, T. Huser, M. Schuettpelz

The paper presents a polymer-based photonic waveguide chip enabling dual-color single-molecule localization microscopy in inverted configurations, achieving 23 nm resolution for cytoskeletal structures.

bioRxiv · Nov 29, 2022 · PreprintBiophysics

Sodium sulfite as a switching agent for single molecule based super-resolution optical microscopy

A. K. Engdahl, O. Grauberger, M. Schüttpelz, T. Huser

The paper demonstrates that sodium sulfite can act as a switching agent in super-resolution microscopy, simplifying buffer solutions and enabling techniques like dSTORM and SOFI.

bioRxiv · Oct 11, 2021 · PreprintBiophysics

Recruitment of Env to the HIV-1 T cell virological synapse by targeted and sustained Env recycling

L. Wang, A. Sandmeyer, W. Hübner, H. Li, T. Huser, B. K. Chen

This study investigates how HIV-1 Env is recruited and retained at the virological synapse through targeted recycling rather than irreversible interactions.

bioRxiv · Dec 8, 2020 · PreprintMicrobiology

Deep-learning based denoising and reconstruction of super-resolution structured illumination microscopy images

Z. H. Shah, M. Müller, T.-C. Wang, P. M. Scheidig, A. Schneider, M. Schüttpelz, T. Huser, W. Schenck

This paper develops a deep-learning method to denoise and reconstruct SR-SIM images, improving image quality and robustness across varying noise levels and microscope settings.

bioRxiv · Oct 27, 2020Biophysics

Simulating digital micromirror devices for patterning coherent excitation light in structured illumination microscopy

M. Lachetta, H. Sandmeyer, A. Sandmeyer, J. Schulte am Esch, T. Huser, M. Müller

This paper presents simulation frameworks for DMD-based illumination systems in structured illumination microscopy, addressing diffraction effects and system alignment.

bioRxiv · Oct 2, 2020Biophysics

DMD-based super-resolution structured illumination microscopy visualizes live cell dynamics at high speed and low cost

A. Sandmeyer, M. Lachetta, H. Sandmeyer, W. Hübner, T. Huser, M. Müller

This paper develops a cost-effective, high-speed structured illumination microscopy system using DMDs and CMOS cameras to visualize live cell dynamics with super-resolution.

bioRxiv · Oct 8, 2019 · PreprintBiophysics

High speed multi-plane super-resolution structured illumination microscopy of living cells using an image-splitting prism

A. Descloux, M. Müller, V. Navikas, A. Markwirth, R. Van den Eynde, T. Lukes, W. Hübner, T. Lasser, A. Radenovic, P. Dedecker, T. Huser

This paper introduces a multi-plane SR-SIM technique to enable fast 3D live cell imaging using an image-splitting prism and additional camera.

bioRxiv · Sep 18, 2019 · PreprintBiophysics

Quantitative comparison of camera technologies for cost-effective Super-resolution Optical Fluctuation Imaging (SOFI)

R. Van den Eynde, A. Sandmeyer, W. Vandenberg, S. Duwe, W. Huebner, T. Huser, P. Dedecker, M. Mueller

This study compares camera technologies for cost-effective Super-resolution Optical Fluctuation Imaging (SOFI), showing that industrial-grade detectors can achieve SOFI on standard and home-built microscopes.

bioRxiv · Apr 8, 2019Biophysics

Identification of a human adult cardiac stem cell population with neural crest origin

A. L. Höving, M. Merten, K. E. Schmidt, I. Faust, L. M. Ruiz-Perera, H. Hachmeister, S.-P. Sommer, B. Fujita, T. Pühler, T. Huser, J. F. W. Greiner, B. Kaltschmidt, J. Gummert, C. Knabbe, C. Kaltschmidt

The paper identifies a human adult cardiac stem cell population with neural crest origin and shows its potential to differentiate into multiple cell types.

bioRxiv · Mar 27, 2019 · PreprintCell Biology