T. J. Kawecki

This study identifies a cis-regulatory polymorphism in fiz that contributes to polygenic adaptation to malnutrition in Drosophila melanogaster by modulating ecdysone oxidase activity and larval growth.

This paper shows that Drosophila melanogaster populations adapted to nutrient-poor diets evolved enhanced amino acid catabolism and a trade-off between amino acid use for energy and protein synthesis.

This study investigates the population genomics of an inversion polymorphism in Drosophila melanogaster across four continents, finding evidence of balancing selection and climate-driven distribution patterns.

This study shows that evolutionary adaptation to juvenile malnutrition in Drosophila leads to metabolic changes in adults that impair fitness, suggesting non-independent evolution of juvenile and adult metabolism.

This study identifies genomic regions associated with adaptation to larval malnutrition in Drosophila and finds a trade-off with adult starvation resistance.

This study shows that Drosophila populations adapted to chronic malnutrition rely less on microbiota for digestion and growth, with changes in dFOXO targets.