Bile acid metabolites control Th17 and Treg cell differentiation
S. Hang, D. Paik, S. Devlin, T. Jamma, J. Lu, S. Ha, B. Nelson, S. Kelly, L. Wu, Y. Zheng, F. Rastinejad, M. Krout, M. Fischbach, D. Littman, J. Huh
This study identifies two bile acid metabolites that regulate Th17 and Treg cell differentiation through distinct mechanisms, affecting immune balance in mice.
bioRxiv · Nov 8, 2018Immunology