Author

T. K. Hale

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Organism:human· 2 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

A. E. Rieffer· 1 shared E. Harjes· 1 shared G. B. Jameson· 1 shared H. L. Fitzsimons· 1 shared H. M. Kurup· 1 shared J. Filitcheva· 1 shared J. H. Park· 1 shared M. Bayarjagal· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperCancer Biology

A. E. Rieffer

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Cancer BiologybioRxivFeb 17, 2023

Structure-guided inhibition of the cancer DNA-mutating enzyme APOBEC3A

S. Harjes, H. M. Kurup, A. E. Rieffer…·G. B. Jameson

This paper identifies a structural basis for inhibiting APOBEC3A, a mutagenic enzyme in cancer, using a hairpin DNA inhibitor that blocks its activity in human cells.

DOI 10.1038/s41467-023-42174-w

humanDNA methylation

𝕏 PostBluesky

Cancer BiologybioRxivPreprintMay 30, 2021

EP400NL is required for cMyc-mediated PD-L1 gene activation by forming a transcriptional coactivator complex

Z. Li, H. L. Fitzsimons, T. K. Hale, J. H. Park

The paper shows EP400NL forms a chromatin remodeling complex that activates PD-L1 gene expression via cMyc, suggesting it as a target for cancer immunotherapy.

DOI 10.1101/2021.05.30.446361

humanChIP-seq

𝕏 PostBluesky