ImmunologybioRxivPreprint
Ubiquitin ligase RIPLET mediates polyubiquitination of RIG-I and LGP2 and regulates the innate immune responses to SARS-CoV-2 infection
T. Kouwaki, T. Nishimura, G. Wang…·H. Oshiumi
This study identifies RIPLET as a ubiquitin ligase that activates RIG-I signaling and modulates innate immune responses to SARS-CoV-2 by polyubiquitinating RIG-I and LGP2.
DOI 10.1101/2021.01.25.428042