Author

T. L. Steinacker

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Cell Biology· 5

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Research Focus:cell signaling & trafficking· 5 Organism:Drosophila· 4 Approach:experimental assay· 4 Research Focus:development & morphogenesis· 2 Organism:C. elegans· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

J. W. Raff· 4 shared S. Saurya· 4 shared A. Wainman· 3 shared S.-S. Wong· 3 shared F. Y. Zhou· 2 shared L. Gartenmann· 2 shared M. G. Aydogan· 2 shared M. Mofatteh· 2 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

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4 shared papersCell Biology

J. W. Raff

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5 papers

Recent·Most cited

Centrioles generate two scaffolds with distinct biophysical properties to build mitotic centrosomes

S.-S. Wong, J. M. Monteiro, C.-C. Chang, M. Peng, N. Mohamad, T. L. Steinacker, S. Saurya, A. Wainman, J. W. Raff

The paper shows that Spd-2 recruits Polo and Aurora A to form two distinct scaffolds, Cnn-scaffold and TACC-scaffold, which are essential for mitotic centrosome assembly in Drosophila.

bioRxiv · Apr 9, 2024Cell Biology

Centriole distal-end proteins CP110 and Cep97 influence centriole cartwheel growth at the proximal-end

M. G. Aydogan, L. E. Hankins, T. L. Steinacker, M. Mofatteh, S. Saurya, A. Wainman, S.-S. Wong, X. Lu, F. Y. Zhou, J. W. Raff

The paper shows that CP110 and Cep97 at the distal end of centrioles influence cartwheel growth at the proximal end through interactions with Plk4 oscillations.

Journal of Cell Science · Jul 20, 2022Peer-reviewedCell Biology

Centriole growth is not limited by a finite pool of components, but is limited by the Cdk1/Cyclin-dependent phosphorylation of Ana2/STIL

T. L. Steinacker, S.-S. Wong, Z. A. Novak, S. Saurya, L. Gartenmann, E. J. H. van Houtum, J. R. Sayers, B. C. Lagerholm, J. W. Raff

The paper shows that centriole growth in Drosophila embryos is not limited by component availability but by Cdk1/Cyclin-dependent phosphorylation of Ana2/STIL, which regulates growth timing.

bioRxiv · Feb 15, 2022Cell Biology

A deeply conserved miR-1 dependent regulon supports muscle cell physiology

P. Gutierrez-Perez, E. M. Santillan, T. Lendl, A. C. Schrempf, T. L. Steinacker, M. Asparuhova, M. Brandstetter, D. Haselbach, L. Cochella

This study identifies miR-1 as a regulator of mitochondria and lysosome homeostasis in muscle cells, showing its conserved role in controlling V-ATPase and DCT-1/BNIP3.

bioRxiv · Aug 31, 2020 · PreprintCell Biology

An autonomous oscillator times and executes centriole biogenesis

M. G. Aydogan, T. L. Steinacker, M. Mofatteh, L. Gartenmann, A. Wainman, S. Saurya, S. S. Wong, F. Y. Zhou, M. A. Boemo, J. W. Raff

The paper identifies an autonomous Plk4 oscillator at the base of growing centrioles in Drosophila embryos that times and sets centriole biogenesis duration, independent of the cell cycle.

bioRxiv · Mar 18, 2019 · PreprintCell Biology