Author

T. Mortimer

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cell type annotation· 2 Research Focus:metabolism & bioenergetics· 2 Assay:metabolomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

J. G. Smith· 3 shared K. B. Koronowski· 3 shared P. Petrus· 3 shared P.-S. Welz· 3 shared C. M. Greco· 2 shared M. Vaca-Dempere· 2 shared O. Deryagin· 2 shared P. Baldi· 2 shared

Activity by Year

2022-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersCell Biology

J. G. Smith

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Author profile →

3 papers

Recent·Most cited

Interrogating Metabolic Interactions Between Skeletal Muscle and Liver Circadian Clocks In Vivo

J. G. Smith, K. B. Koronowski, T. Sato, C. Greco, P. Petrus, A. Verlande, S. Chen, M. Samad, E. Deyneka, L. Mathur, R. Blazev, J. Molendijk, T. Mortimer, A. Kumar, O. Deryagin, , P. Sassone-Corsi

The paper investigates the role of circadian clocks in liver and skeletal muscle in glucose metabolism, finding that inter-organ communication is necessary for systemic glucose homeostasis.

bioRxiv · Feb 27, 2022Cell Biology

Epidermal clock integration and gating of brain signals guarantees skin homeostasis

T. Mortimer, V. M. Zinna, M. Atalay, C. Laudanna, O. Deryagin, J. G. Smith, E. Garcia-Lara, M. Vaca-Dempere, K. B. Koronowski, P. Petrus, C. M. Greco, S. Forrow, P. Sassone Corsi, P.-S. Welz, P. Munoz Canoves, S. Aznar Benitah

The paper identifies a gatekeeping function of the epidermal clock in integrating and correcting brain signals to maintain skin homeostasis.

bioRxiv · Jan 26, 2022 · PreprintCell Biology

The central clock suffices to drive the majority of circulatory metabolic rhythms

P. Petrus, J. G. Smith, K. B. Koronowski, S. Chen, T. Sato, C. M. Greco, T. Mortimer, P.-S. Welz, V. M. Zinna, K. Shimaji, M. Cervantes, P. Baldi, P. M. Canoves, P. Sassone-Corsi, S. A. Benitah

The study shows that the central clock, via Syt10-expressing neurons, drives most circulatory metabolic rhythms and rescues glucose intolerance, highlighting its role in circadian communication.

bioRxiv · Jan 24, 2022Physiology