ImmunologybioRxiv
CD8 T cells induce destruction of bone marrow stromal niches and hematopoietic stem cell dysfunction in chronic viral infections
S. Isringhausen, L. Kovtonyuk, U. Suessbier…·C. Nombela-Arrieta
This study shows chronic viral infections impair bone marrow stromal networks and HSC function via CD8 T cell-mediated inflammation.
DOI 10.1084/jem.20192070