Author

T. Patriarchi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Bioengineering· 1

Signature Assays, Organisms & Methods

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Research Focus:protein folding & dynamics· 2 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Assay:fluorescence / live-cell microscopy· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Gresch· 1 shared D. Benke· 1 shared D. Keri· 1 shared E. T. Williams· 1 shared K. Zacharoula· 1 shared L. Duffet· 1 shared M. A. Bhat· 1 shared N. Hartrampf· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBiochemistry

A. Gresch

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Author profile →

2 papers

Recent·Most cited

BiochemistrybioRxivPreprintFeb 14, 2023

Optical tools for visualizing and controlling human GLP-1 receptor activation with high spatiotemporal resolution

L. Duffet, E. T. Williams, A. Gresch…·T. Patriarchi

This paper introduces GLPLight1, a genetically-encoded sensor for high spatiotemporal resolution visualization of GLP1R activation, and demonstrates its use in optical control of receptor activation.

DOI 10.1101/2023.02.14.528498

humanfluorescence / live-cell microscopy

𝕏 PostBluesky

BioengineeringbioRxivPreprintSep 21, 2021

Computationally-guided tuning of ligand sensitivity in a GPCR-based sensor

D. Keri, R. B. Cola, K. Zacharoula…·P. Barth

The paper enhances the sensitivity of a GPCR-based dopamine sensor using computational design, achieving up to 15-fold increased potency for norepinephrine.

DOI 10.1101/2021.09.21.461282

proteomicsdeep learning

𝕏 PostBluesky