Cancer BiologybioRxiv
Glucose deprivation promotes pseudo-hypoxia and de-differentiation in lung adenocarcinoma
P. Saggese, A. Pandey, E. Fung…·C. Scafoglio
This study shows glucose deprivation in lung adenocarcinoma causes de-differentiation and an aggressive phenotype through epigenetic changes and HIF1 activation.
DOI 10.1158/0008-5472.can-23-1148