Cancer BiologybioRxiv
Doxorubicin-Induced p53 Interferes with Mitophagy in Cardiac Fibroblasts
This study shows doxorubicin increases p53 expression, sequesters Parkin, and reduces mitophagy in cardiac fibroblasts, leading to mitochondrial dysfunction and impaired migration.
DOI 10.1371/journal.pone.0238856