Author

T. Sumida

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Microbiology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 5 Approach:experimental assay· 4 Assay:bulk RNA-seq· 3 Organism:mouse· 3 Approach:statistical model· 3 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Assay:metagenomics· 2

Frequent Co-Authors

T. Nunoura· 3 shared S. Hiraoka· 2 shared A. Ishiwata· 1 shared A. L. Perdigoto· 1 shared A. T. Naito· 1 shared A. Toyoda· 1 shared C. M. Ukeje· 1 shared D. A. Hafler· 1 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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3 shared papersMicrobiology

T. Nunoura

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Development of a rapid and highly accurate method for 13C tracer-based metabolomics and its application on a hydrogenotrophic methanogen

Y. Fukuyama, S. Shimamura, S. Sakai, Y. Michimori, T. Sumida, Y. Chikaraishi, H. Atomi, T. Nunoura

The paper develops a CE-MS method for 13C tracer-based metabolomics and applies it to identify central carbon metabolism and amino acid biosynthesis in a methanogen.

bioRxiv · Aug 31, 2023 · PreprintMicrobiology

Genetic and functional diversity of beta-N-acetylgalactosamine residue-targeting glycosidases expanded by deep-sea metagenome

T. Sumida, S. Hiraoka, K. Usui, A. Ishiwata, T. Sengoku, K. A. Stubbs, K. Tanaka, S. Deguchi, S. Fushinobu, T. Nunoura

This study identifies and characterizes novel beta-N-acetylgalactosaminidases from deep-sea metagenomes, revealing structural diversity and substrate specificity expansion.

bioRxiv · Jul 28, 2023Biochemistry

Diverse DNA modification in marine prokaryotic and viral communities

S. Hiraoka, T. Sumida, M. Hirai, A. Toyoda, S. Kawagucci, T. Yokokawa, T. Nunoura

The paper identifies diverse DNA modifications in marine prokaryotic and viral communities using metaepigenomic analysis and reveals novel MTase-motif pairs and conserved motifs in Alphaproteobacteria.

bioRxiv · May 8, 2021Microbiology

Tet2 Controls Beta cells Responses to Inflammation in Type 1 Diabetes

J. Rui, S. Deng, G. Ponath, R. Kursawe, N. Lawlor, T. Sumida, M. Levine-Ritterman, A. L. Perdigoto, M. L. Stitzel, D. L. Pitt, J. Lu, K. C. Herold

This study identifies Tet2's role in regulating β cell responses to inflammation in Type 1 Diabetes, showing its protective effects against immune-mediated destruction.

bioRxiv · Sep 1, 2020 · PreprintImmunology

SMAD3 Determines Conventional versus Plasmacytoid Dendritic Cell Fates

J.-H. Yoon, E. Bae, K. Sudo, J. S. Han, S. H. Park, S. Nakae, T. Yamashita, I.-K. Lee, J. H. Ju, I. Matsumoto, T. Sumida, M. Kuroda, K. Miyazawa, M. Kato, M. Mamura

This study identifies SMAD3 as a key regulator determining conventional DC versus plasmacytoid DC differentiation through distinct gene regulatory mechanisms.

bioRxiv · Jul 25, 2019 · PreprintImmunology

PTGER2-β-Catenin Axis Links High Salt Environments to Autoimmunity by Balancing IFNγ and IL-10 in FoxP3+ Regulatory T cells

T. Sumida, M. R. Lincoln, C. M. Ukeje, D. M. Rodriguez, H. Akazawa, T. Noda, A. T. Naito, I. Komuro, M. Dominguez-Villar, D. A. Hafler

The paper identifies a PTGER2-β-catenin axis that balances IFNγ and IL-10 in FoxP3+ Tregs, linking high salt environments to autoimmunity.

bioRxiv · Aug 2, 2018 · PreprintImmunology