Author

M. L. Stitzel

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Approach:statistical model· 2 Assay:CITE-seq· 1 Approach:deep learning· 1 Approach:experimental assay· 1

Frequent Co-Authors

N. Lawlor· 2 shared A. L. Perdigoto· 1 shared A. Lietzke· 1 shared A. M. Stendahl· 1 shared A. Renberg· 1 shared A. Williams· 1 shared B. A. Kaufman· 1 shared B. Thompson· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersCell Biology

N. Lawlor

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Retrograde mitochondrial signaling governs the identity and maturity of metabolic tissues

G. L. Pearson, E. M. Walker, N. Lawlor, A. Lietzke, V. Sidarala, J. Zhu, T. Stromer, E. C. Reck, A. M. Stendahl, J. Li, E. Levi-D'Ancona, M. B. Pasmooij, D. L. Hubers, A. Renberg, K. Mohamed, , S. A. Soleimanpour

This study shows that mitochondrial dysfunction triggers a retrograde signaling program that reduces cellular maturity in metabolic tissues, and blocking this signaling can restore cell identity and improve hyperglycemia.

bioRxiv · Aug 2, 2022 · PreprintCell Biology

Single cell analysis of blood mononuclear cells stimulated through CD3 and CD28 shows collateral activation of B and NK cells and demise of monocytes

N. T. Lawlor, D. Nehar-Belaid, J. Grassmann, M. Stoeckius, P. Smibert, M. L. Stitzel, V. Pascual, J. Banchereau, A. Williams, D. Ucar

The paper uses single-cell RNA-seq and CITE-seq to analyze PBMC responses to T-cell and monocyte activators, showing differential activation patterns and transcriptional changes in various immune cell types.

bioRxiv · Dec 23, 2020 · PreprintImmunology

Tet2 Controls Beta cells Responses to Inflammation in Type 1 Diabetes

J. Rui, S. Deng, G. Ponath, R. Kursawe, N. Lawlor, T. Sumida, M. Levine-Ritterman, A. L. Perdigoto, M. L. Stitzel, D. L. Pitt, J. Lu, K. C. Herold

This study identifies Tet2's role in regulating β cell responses to inflammation in Type 1 Diabetes, showing its protective effects against immune-mediated destruction.

bioRxiv · Sep 1, 2020 · PreprintImmunology