Author

T. Tabata

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Biophysics· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:human· 4 Research Focus:cell type annotation· 2 Research Focus:drug response / drug discovery· 2 Research Focus:host-pathogen & immune response· 2 Assay:proteomics· 2 Research Focus:gene regulatory network inference· 1 Assay:protein structure· 1

Frequent Co-Authors

A. M. Syed· 3 shared J. A. Doudna· 3 shared M. M. Khalid· 3 shared M. Ott· 3 shared T. Y. Taha· 3 shared A. Ciling· 2 shared G. R. Kumar· 2 shared I. P. Chen· 2 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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Curved chords = mutual co-authorship

3 shared papersMicrobiology

A. M. Syed

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Regulation of virion production by the ORF8 signal peptide across SARS-CoV-2 variants

M. M. Khalid, I. Chen, F. S. Soveg, T. Y. Taha, T. Tabata, R. Suryawanshi, A. M. Syed, A. Ciling, M. McCavitt-Malvido, U. Schulze-Gahmen, J. Hayashi, I.-J. Kim, S. W. Fong, J. Batra, G. R. Kumar, , M. Ott

This study shows ORF8 suppresses viral particle production by interacting with Spike and causing Golgi fragmentation, supporting evolutionary pressure to delete ORF8 in SARS-CoV-2 variants.

bioRxiv · Mar 5, 2024 · PreprintMicrobiology

Rapid assembly of SARS-CoV-2 genomes reveals attenuation of the Omicron BA.1 variant through NSP6

T. Y. Taha, I. P. Chen, J. M. Hayashi, T. Tabata, K. Walcott, G. R. Kimmerly, A. M. Syed, A. Ciling, R. K. Suryawanshi, H. S. Martin, B. H. Bach, C.-L. Tsou, M. Montano, M. M. Khalid, B. K. Sreekumar, , M. Ott

The paper introduces a plasmid-based method to assemble SARS-CoV-2 genomes and identifies NSP6 mutations as causing Omicron attenuation.

bioRxiv · Jan 31, 2023 · PreprintMicrobiology

A stress-reduced passaging technique improves the viability of human pluripotent cells

K. Takahashi, C. Okubo, M. Nakamura, M. Iwasaki, Y. Kawahara, T. Tabata, Y. Miyamoto, K. Woltjen, S. Yamanaka

This paper introduces a stress-reduced passaging technique for human pluripotent stem cells that improves viability and downstream application efficiency without altering cell characteristics.

bioRxiv · Oct 12, 2021Cell Biology

Rapid assessment of SARS-CoV-2 evolved variants using virus-like particles

A. M. Syed, T. Y. Taha, M. M. Khalid, T. Tabata, I. P. Chen, B. Sreekumar, P.-Y. Chen, J. M. Hayashi, K. M. Soczek, M. Ott, J. A. Doudna

This study uses SARS-CoV-2 virus-like particles to rapidly assess mutations in viral variants, finding that N protein mutations enhance RNA packaging and viral spread.

bioRxiv · Aug 5, 2021Microbiology

Crystal structure of inhibitor-bound human MSPL that can activate high pathogenic avian influenza

A. Ohno, N. Maita, T. Tabata, H. Nagano, K. Arita, M. Ariyoshi, T. Uchida, R. Nakao, A. Ulla, K. Sugiura, K. Kishimoto, S. Teshima-Kondo, Y. Okumura, T. Nikawa

The paper determines the crystal structure of human MSPL bound to an inhibitor, revealing key residues involved in substrate recognition and providing a homology model for TMPRSS2.

bioRxiv · Jun 12, 2020Biophysics