T. Takaya

This study shows that the myogenetic oligodeoxynucleotide iSN04 induces cardiomyocyte differentiation from murine pluripotent stem cells by modulating Wnt signaling and inhibiting nucleolin.

This study shows that iSN04, an anti-nucleolin aptamer, reduces inflammation in myoblasts by inhibiting the β-catenin/NF-κB pathway.

The paper identifies an ODN, iSN40, that promotes osteoblast differentiation and calcification without relying on TLR9.

This study shows that the oligodeoxynucleotide iSN04 restores myoblast differentiation and reverses inflammation caused by cancer-conditioned medium.

This study shows that anti-nucleolin aptamers iSN04 and AS1411 inhibit the growth of embryonal rhabdomyosarcoma cells by targeting nucleolin expression.

This study shows that myogenetic oligodeoxynucleotides (myoDNs) can restore myoblast differentiation in diabetes mellitus patients by reducing myostatin and interleukin-8.

This study shows that myogenetic oligodeoxynucleotides (myoDNs) enhance chicken myoblast differentiation, with the iSN04-berberine complex showing increased activity in myotube formation and myogenic gene expression.

The paper identifies bacterial-derived oligodeoxynucleotides (myoDNs) that promote skeletal muscle myoblast differentiation by targeting nucleolin.