Author

T. V. Sharp

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

F. K. Mardakheh· 2 shared A. Bhamra· 1 shared D. Pezic· 1 shared K. Davidson· 1 shared K. M. Shah· 1 shared K. S. Bridge· 1 shared K. Shah· 1 shared M. Contreras· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCell Biology

F. K. Mardakheh

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

STAG3 promotes exit from pluripotency through post-transcriptional mRNA regulation in the cytoplasm.

S. Weeks, D. Pezic, M. Dodel, K. Shah, A. Bhamra, S. Surinova, S. Henderson, T. V. Sharp, F. K. Mardakheh, S. HADJUR

This study shows STAG3 regulates post-transcriptional mRNA in mESCs, promoting exit from pluripotency by interacting with RNA-binding proteins and affecting mRNA stability.

bioRxiv · May 31, 2024 · PreprintCell Biology

Targeted therapy for LIMD1-deficient non-small cell lung cancer subtypes.

K. Davidson, P. Grevitt, M. Contreras, K. S. Bridge, M. Hermida, K. M. Shah, F. K. Mardakheh, M. Stubbs, P. A. Clarke, R. Burke, P. Casado-Izquierdo, P. R. Cutillas, S. A. Martin, T. V. Sharp

This paper identifies PF-477736 as a selective cytotoxic compound for LIMD1-deficient NSCLC cells and xenograft models, offering a potential targeted therapy for this understudied cancer subtype.

bioRxiv · Feb 1, 2021Cancer Biology