STAG3 promotes exit from pluripotency through post-transcriptional mRNA regulation in the cytoplasm.
S. Weeks, D. Pezic, M. Dodel, K. Shah, A. Bhamra, S. Surinova, S. Henderson, T. V. Sharp, F. K. Mardakheh, S. HADJUR
This study shows STAG3 regulates post-transcriptional mRNA in mESCs, promoting exit from pluripotency by interacting with RNA-binding proteins and affecting mRNA stability.
bioRxiv · May 31, 2024 · PreprintCell Biology