Author

T. X. McCallister

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Assay:CRISPR screen· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1 Organism:mouse· 1 Research Focus:perturbation response prediction· 1

Frequent Co-Authors

C. Cotton· 1 shared C. K. W. Lim· 1 shared C. Saporito-Magrina· 1 shared D. Dacus· 1 shared E. Rigiofoirate· 1 shared G. D. McPheron· 1 shared J. E. Powell· 1 shared L. V. Clark· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

C. Cotton

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

BioengineeringbioRxivPreprintMay 26, 2022

CRISPR base editing of cis-regulatory elements enables target gene perturbations

C. K. W. Lim, T. X. McCallister, C. Saporito-Magrina…·T. Gaj

This study shows CRISPR base editors can reduce gene expression by editing cis-regulatory elements, with examples in human and mouse models.

DOI 10.1101/2022.05.26.493649

𝕏 PostBluesky

Cancer BiologybioRxivPreprintSep 6, 2019

β-HPV 8E6 Dysregulates the Hippo Signaling Pathway and Induces Aneuploidy

D. Dacus, T. X. McCallister, C. Cotton…·N. A. Wallace

This paper shows that β-HPV 8E6 disrupts the Hippo signaling pathway, leading to increased cell growth and aneuploidy, and synergizes with telomerase activation to promote genomic instability.

DOI 10.1101/760439

humanexperimental assay

𝕏 PostBluesky