S. Murakami

Selenocysteine tRNA methylation promotes oxidative stress resistance in melanoma metastasis

This study shows that FTSJ1-mediated tRNASec methylation enhances oxidative stress resistance and metastatic colonization in melanoma.

Isolation of bat sarbecoviruses of SARS-CoV-2 clade, Japan

The paper isolates and characterizes SARS-CoV-2 clade sarbecoviruses from Japanese bats, showing host-specific replication and genetic variation in the S1 region.

Influenza A virus agnostic receptor tropism revealed using a novel biological system with terminal sialic acid-knockout cells

This paper introduces a novel system using sialic acid receptor-knockout cells to study influenza A virus receptor tropism, revealing unique biological tropism undetectable by conventional assays.

Taurine suppresses liquid-liquid phase separation of lysozyme protein

This study shows taurine reduces liquid-liquid phase separation in lysozyme solutions under specific conditions.

Puerarin blocks aging phenotype in cultured human dermal fibroblasts

This study shows puerarin prevents aging-related changes in human dermal fibroblasts by reducing senescence and myofibroblast markers.

Establishment of a Reverse Genetics System for Influenza D Virus

This paper establishes a reverse genetics system for Influenza D virus, enabling the generation of recombinant viruses and analysis of replication and pathogenicity mechanisms.

Energetics and Conformational Pathways of Functional Rotation in the Multidrug Transporter AcrB

This study calculates the minimum free energy pathway of functional rotation in AcrB, linking it to proton translocation and drug transport at the atomic level.