T. Yashiro

This study identifies 10-oxo-cis-6,trans-11-octadecadienoic acid as an anti-inflammatory metabolite that suppresses colitis in mice via NRF2 pathway activation and GPCR signaling.

This study evaluates the immunomodulating effects of Bacillus coagulans SANK70258, showing it induces high IFN-γ and IgA production compared to other lactic acid bacteria.

This study shows kaempferol suppresses mast cell activation by reducing FcεRI surface expression and increasing SHIP1 levels, independent of transcription and translation.

This study shows that butyrate and valerate reduce IgE-mediated mast cell activation by enhancing PGE2 release and GPR109A signaling, while niacin also alleviates anaphylaxis through similar mechanisms.

This study shows that β-damascone, a rose compound, activates the NRF2 pathway in dendritic cells to reduce immune responses and alleviate contact hypersensitivity in mice.