M. Ando

NR4A3 deficiency ameliorates contact hypersensitivity and exacerbates psoriasis by regulating gene expression in dendritic cells

This study shows NR4A3 deficiency reduces contact hypersensitivity but worsens psoriasis by altering dendritic cell gene expression.

Artificial Intelligence Enables the Label-Free Identification of Chronic Myeloid Leukemia Cells with Mitochondrial Morphological Alterations

This study uses AI with flow cytometry to identify CML cells with mitochondrial morphological changes, enabling early diagnosis and monitoring of treatment response.

The gut lactic acid bacteria metabolite, 10-oxo-cis-6,trans-11-octadecadienoic acid, suppresses inflammatory bowel disease in mice by modulating the NRF2 pathway and GPCR-signaling

This study identifies 10-oxo-cis-6,trans-11-octadecadienoic acid as an anti-inflammatory metabolite that suppresses colitis in mice via NRF2 pathway activation and GPCR signaling.

Kaempferol suppresses the activation of mast cells by modulating the expression of FcϵRI and SHIP1

This study shows kaempferol suppresses mast cell activation by reducing FcεRI surface expression and increasing SHIP1 levels, independent of transcription and translation.

Butyrate, valerate, and niacin ameliorate anaphylaxis by suppressing IgE-dependent mast cell activation: Roles of GPR109A, PGE2, and epigenetic regulation

This study shows that butyrate and valerate reduce IgE-mediated mast cell activation by enhancing PGE2 release and GPR109A signaling, while niacin also alleviates anaphylaxis through similar mechanisms.

Mycelial differentiation linked avermectin production in studied with Raman imaging

This study uses Raman imaging to show how avermectin production correlates with mycelial differentiation stages in Streptomyces avermitilis under different culture conditions.

Memory B cells and memory T cells induced by SARS-CoV-2 booster vaccination or infection show different dynamics and efficacy to the Omicron variant.

A rose flavor compound activating the NRF2 pathway in dendritic cells ameliorates contact hypersensitivity in mice

This study shows that β-damascone, a rose compound, activates the NRF2 pathway in dendritic cells to reduce immune responses and alleviate contact hypersensitivity in mice.

Aberrant mechanosensitive signaling underlies activation of vascular endothelial xanthine oxidoreductase that promotes aortic aneurysm formation in Marfan syndrome

This study identifies aberrant mechanosensitive signaling in vascular endothelial cells as a driver of xanthine oxidoreductase activation and ROS generation, contributing to aortic aneurysm formation in Marfan syndrome.

Raman microspectroscopy imaging analysis of extracellular vesicles (EVs) biogenesis by filamentous fungus Penicilium chrysogenum

This study uses Raman microspectroscopy to investigate EV biogenesis in Penicillium chrysogenum and shows EVs release penicillin.

Single-cell metabolite detection and genomics reveals uncultivated talented producer

This study identifies an uncultivated bacterium as a producer of antifungal metabolites using Raman microscopy and single-cell sequencing in a sponge microbiome.

Detection of Penicillin G Produced by Penicillium chrysogenum KF 425 in Vivo with Raman Microspectroscopy and Multivariate Curve Resolution-Alternating Least Squares Methods

This study detects penicillin G inside Penicillium chrysogenum KF425 cells using Raman microspectroscopy and MCR-ALS, revealing its subcellular localization for the first time.

Molecular profiling of lipid droplets inside HuH7 Cells with Raman micro-spectroscopy

This study uses Raman micro-spectroscopy with multivariate curve resolution to profile lipid droplet molecular composition in HuH7 cells, revealing structural changes related to cellular physiology.

Molecular mechanisms for intestinal HCO3- secretion and its regulation by guanylin in seawater-acclimated eels

This study identifies molecular mechanisms of HCO3- secretion in seawater-acclimated eels, showing guanylin inhibits NKCC2 and activates DRA and NBC transporters to enhance HCO3- flux.