Author

Takanori Miyamoto

Chiba Cancer Center Research Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1

Frequent Co-Authors

Hiroyuki KogashiiD· 1 shared Kazuma NakataniiD· 1 shared Kazuto KugouiD· 1 shared Taiki Setoguchi· 1 shared Takashi YamamotoiD· 1 shared Tetsushi SakumaiD· 1 shared Yoshinori HasegawaiD· 1 shared Yoshitaka HippoiD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 36 mutual co-author links

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1 shared paperCancer Biology

Hiroyuki KogashiORCID

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1 paper

Recent·Most cited

Cancer BiologyFrontiers in OncologyPeer-reviewedFeb 8, 2024

Inhibition of OCT4 Binding at the MYCN Locus Induces Neuroblastoma Cell Death Accompanied by Downregulation of Transcripts with High-Open Reading Frame Dominance

Kazuma Nakatani, Hiroyuki Kogashi, Takanori Miyamoto…·Yusuke Suenaga

This study shows that inhibiting OCT4 binding at the MYCN locus in neuroblastoma cells reduces MYCN activity, leading to cell death through caspase-2 activation and downregulation of high-ORF dominance transcripts.

8 citations

humanbulk RNA-seq

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