BiophysicsJournal of Molecular BiologyPeer-reviewed
Mechanistic modeling of amyloid oligomer and protofibril formation
Keisuke Yuzu, Hiroshi Imamura, Takuro Nozaki…·Eri Chatani
This study establishes a mechanistic model of amyloid oligomer and protofibril formation in bovine insulin using light scattering and kinetic analysis, revealing end-to-end association as the rate-limiting step.
2 citations