Eri Chatani

The paper investigates how temperature sensitivity in phase separation of an intrinsically disordered protein is encoded by local aromatic interactions, showing that tyrosine residues mediate both structural stability and phase behavior.

This study establishes a mechanistic model of amyloid oligomer and protofibril formation in bovine insulin using light scattering and kinetic analysis, revealing end-to-end association as the rate-limiting step.