BiochemistryeLifePeer-reviewed
Structural dynamics of the active HER4 and HER2/HER4 complexes is finely tuned by different growth factors and glycosylation
Raphael Trenker, Devan C. Diwanji, Tanner Bingham…·Natalia Jura
This study reports cryo-EM structures of HER2/HER4 heterodimers and HER4 homodimers bound to different ligands, revealing structural dynamics and glycan contributions to receptor activation.
28 citations