Developmental BiologybioRxiv
Epigenetic reprogramming induced by Acetyl-CoA and SAM depletion is an evolutionarily-ancient path to malignant growth
Zhe Chen, Xiaomeng Zhang, Mingxi Deng…·Yan Yan
This study identifies common metabolic and epigenetic changes in fly and human tumors, showing that metabolite depletion drives tumorigenesis across species.
DOI 10.14711/thesis-hdl152380