Cell BiologyScience AdvancesPeer-reviewed
Senataxin and DNA-PKcs Redundantly Promote Non-Homologous End Joining Repair of DNA Double Strand Breaks During V(D)J Recombination
Bo-Ruei Chen, Thu N. Pham, Lance Dylan Reynolds…·Barry P. Sleckman
The paper shows senataxin and DNA-PKcs redundantly support NHEJ repair of RAG-induced DSBs during V(D)J recombination, with senataxin's function overlapping with RECQL5 and HLTF.
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