Author

Tong‐Yao Gao

Zhejiang University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:protein folding & dynamics· 2 Assay:proteomics· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:differential expression· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

Chun TangiD· 2 shared Cong CheniD· 2 shared Hua-Wei YiiD· 2 shared Tao-Feng WeiiD· 2 shared Tong WangiD· 2 shared Wei‐Ping ZhangiD· 2 shared Yi ZhangiD· 2 shared Yun‐Bi LuiD· 2 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 44 mutual co-author links

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2 shared papersBiochemistry

Chun TangORCID

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2 papers

Recent·Most cited

BiochemistryeLifePeer-reviewedJul 31, 2025

Elevated Ubiquitin Phosphorylation by PINK1 Contributes to Proteasomal Impairment and Promotes Neurodegeneration

Cong Chen, Tong‐Yao Gao, Hua-Wei Yi…·Wei‐Ping Zhang

This study shows that elevated phosphorylated ubiquitin (pUb) caused by PINK1 impairs proteasomal activity and promotes neurodegeneration in multiple conditions.

7 citations

mouseproteomics

𝕏 PostBluesky

Cell BiologybioRxivPreprintAug 10, 2023

Ubiquitin phosphorylation accelerates protein aggregation and promotes neurodegeneration in the aging brain

Cong Chen, Hua-Wei Yi, Yi Zhang…·Chun Tang

This study shows that phosphorylated ubiquitin (pUb) increases with age and contributes to neurodegeneration by impairing proteasomal function and accelerating protein aggregation.

DOI 10.1101/2023.08.10.552882

mouseproteomics

𝕏 PostBluesky