Developmental BiologybioRxivPreprint
Direct reprogramming of adult hepatocytes to generate LGR5+ endodermal progenitor
Diana Chaker, Christophe Desterke, Nicolas Moniaux…·Frank Griscelli
This paper describes a method to convert adult hepatocytes into LGR5+ endodermal progenitor cells using transcription factors and activators, enabling liver tissue regeneration and disease modeling.
DOI 10.1101/2020.05.29.123273