Author

U. Phan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Assay:proteomics· 2 Approach:biophysical modeling· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

A. W. Partridge· 2 shared B. Henry· 2 shared P. Gopal· 2 shared R. Mangadu· 2 shared S. C. Chang· 2 shared S. Lim· 2 shared S. Ng· 2 shared A. C. N. Sim· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCell Biology

A. W. Partridge

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Targeted degradation of PCNA outperforms stoichiometric inhibition to result in programed cell death

S. C. Chang, P. Gopal, S. Lim, X. Wei, R. Mangadu, J. Smith, S. Ng, M. Gindy, U. Phan, B. Henry, A. W. Partridge

This study shows that targeted degradation of PCNA via biodegraders leads to more effective anti-proliferative effects and programmed cell death compared to stoichiometric inhibition.

bioRxiv · Jan 29, 2022Cell Biology

STUB1 is an intracellular checkpoint for interferon gamma sensing

S. Ng, S. Lim, A. C. N. Sim, R. Mangadu, A. Lau, C. Zhang, S. Bollinger Martinez, A. Chandramohan, U.-M. Lim, S. S. W. Ho, S. C. Chang, P. Gopal, L. Z. Hong, A. Schwaid, A. Z. Fernandis, , A. W. Partridge

This study identifies STUB1 as a barrier to interferon gamma sensing, showing it dampens IFNγ response through reduced IFNGR1 surface abundance, but in vivo STUB1 inactivation did not improve ICB outcomes in mouse models.

bioRxiv · Dec 14, 2020Cancer Biology