MicrobiologybioRxivPreprint
Subgenomic SARS-CoV-2 replicon and reporter replicon cell lines enable ultrahigh throughput antiviral screening and mechanistic studies with antivirals, viral mutations or host factors that affect COVID-19 replication
S. Lan, P. R. Tedbury, Y. T. Ong…·S. G. Sarafianos
This paper develops SARS-CoV-2 replicon systems and cell lines for antiviral screening and mechanistic studies, enabling research at lower biosafety levels.
DOI 10.1101/2021.12.29.474471