Author

S. Lan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Bioengineering· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:drug response / drug discovery· 2 Organism:human· 2

Frequent Co-Authors

H. Zhang· 2 shared M. E. Cilento· 2 shared P. R. Tedbury· 2 shared R. L. Slack· 2 shared S. G. Sarafianos· 2 shared W. A. Cantara· 2 shared A. Emanuelli Castaner· 1 shared E. A. Boggs· 1 shared

Activity by Year

2021-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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2 shared papersMicrobiology

H. Zhang

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Nirmatrelvir Resistance in SARS-CoV-2 Omicron_BA.1 and WA1 Replicons and Escape Strategies

S. Lan, G. Neilsen, R. L. Slack, W. A. Cantara, A. Emanuelli Castaner, Z. C. Lorson, N. D. Lulkin, H. Zhang, J. Lee, M. E. Cilento, P. R. Tedbury, S. G. Sarafianos

This study identifies E166V as a key mutation conferring high nirmatrelvir resistance in SARS-CoV-2, with differential effects on Omicron and WA1 variants, and explores strategies to overcome resistance.

bioRxiv · Dec 31, 2022 · PreprintMicrobiology

Superparamagnetic iron oxide enclosed hollow gold nanostructure with tunable surface plasmon resonances to promote near-infrared photothermal conversion

M. Yuan, X. Feng, T.-H. Yan, J. Chen, X. Ma, P. Cunha, S. Lan, Y. Li, H.-C. Zhou, Y. Wang

This paper designs and synthesizes SPIO-HGNS nanoparticles with tunable SPR in the NIR range to enhance photothermal conversion for potential photothermal therapies.

bioRxiv · Feb 7, 2022Bioengineering

Subgenomic SARS-CoV-2 replicon and reporter replicon cell lines enable ultrahigh throughput antiviral screening and mechanistic studies with antivirals, viral mutations or host factors that affect COVID-19 replication

S. Lan, P. R. Tedbury, Y. T. Ong, R. Shah, R. L. Slack, M. E. Cilento, H. Zhang, H. Du, N. Lulkin, U. Q. Le, K. A. Kirby, I. Melcak, W. A. Cantara, E. A. Boggs, S. G. Sarafianos

This paper develops SARS-CoV-2 replicon systems and cell lines for antiviral screening and mechanistic studies, enabling research at lower biosafety levels.

bioRxiv · Dec 29, 2021 · PreprintMicrobiology