U. Theopold

Single-cell sequencing of tumor-associated macrophages in a Drosophila model.

The paper uses a Drosophila model to study tumor-associated macrophages via single-cell RNA-sequencing, identifying distinct hemocyte clusters and their differential gene expression in tumor versus wild-type larvae.

Chitinase-like proteins promoting tumorigenesis through disruption of cell polarity via enlarged endosomal vesicles.

This study identifies Idgf3, a chitinase-like protein, as promoting tumorigenesis in Drosophila by disrupting cell polarity through enlarged endosomal vesicles.

Anti-fibrotic activity of an antimicrobial peptide in a Drosophila model.

This study shows that overexpression of the Ras oncogene in Drosophila salivary glands causes fibrotic lesions, which are reduced by the antimicrobial peptide Drosomycin.

The consequences of surviving infection across the metamorphic boundary: tradeoff insights from RNAseq and life history measures

This study investigates the long-term effects of bacterial infection and injury across metamorphosis in Pieris napi butterflies, finding that infection costs persist into adulthood and negatively impact fitness.

Geographic variation in hemocyte diversity and phagocytic propensity shows a diffuse genomic signature in the green veined white butterfly

The paper examines geographic variation in hemocyte diversity and phagocytic propensity in two butterfly populations, finding phenotypic differences without genetic divergence in phagocytosis-related genes.

Tissue-autonomous immune response regulates stress signalling during hypertrophy

The paper investigates how a tissue-autonomous immune response modulates stress signaling during hypertrophy in Drosophila salivary glands, revealing a role for Drosomycin in inhibiting JNK signaling and preventing programmed cell death.