M. Mohammed

Angiotensin-(1-5) is a Potent Endogenous Angiotensin AT2-Receptor Agonist

This study identifies angiotensin-(1-5) as a potent endogenous agonist of the AT2-receptor, showing its ability to increase nitric oxide release and lower blood pressure through AT2R-mediated mechanisms.

Single-cell sequencing of tumor-associated macrophages in a Drosophila model.

The paper uses a Drosophila model to study tumor-associated macrophages via single-cell RNA-sequencing, identifying distinct hemocyte clusters and their differential gene expression in tumor versus wild-type larvae.

scDual-Seq of Toxoplasma gondii-infected mouse bone marrow-derived dendritic cells reveals host cell heterogeneity and differential infection dynamics

The paper uses Dual-scSeq to analyze T. gondii-infected BMDCs, revealing differential infection dynamics and host-parasite gene interactions.

Single-cell transcriptomics to define Plasmodium falciparum stage-transition in the mosquito midgut

This study uses single-cell transcriptomics to analyze Plasmodium falciparum development in the mosquito midgut, identifying transcriptional trajectories and stress responses, including genes encoding intrinsically disordered proteins.

Discovery of small molecule antagonists of human Retinoblastoma Binding Protein 4 (RBBP4)

This study identifies small molecule antagonists of RBBP4's top pocket, competes with protein and histone interactions, and reports the first crystal structure of RBBP4 with a small molecule.

Coexistence patterns and diversity in a trait-based metacommunity on an environmental gradient

This study uses a spatially-explicit model to show how dispersal and environmental variability influence coexistence patterns and diversity in a trait-based metacommunity.

Single-cell analysis of mosquito hemocytes identifies signatures of immune cell sub-types and cell differentiation

The paper uses scRNA-seq to identify immune cell subtypes and differentiation in mosquitoes, defining markers and showing the role of lozenge in oenocytoid fate.

Metal-Assisted and Microwave-Accelerated Germination

This paper demonstrates a method using gold nanoparticles and microwave heating to accelerate basil plant growth and extend its lifespan.

In silico analysis of CDC73 gene revealing 11 novel SNPs associated with Jaw Tumor Syndrome

The paper uses in-silico tools to analyze CDC73 SNPs and identifies 11 novel variants associated with Jaw Tumor Syndrome.

In silico analysis of IDH3A gene revealed Novel mutations associated with Retinitis Pigmentosa

The paper identifies 20 novel deleterious SNPs in the IDH3A gene associated with Retinitis Pigmentosa using bioinformatics tools.