Cell BiologybioRxivPreprint
The E3 Ubiquitin Ligase Nedd4L Acts as a Checkpoint Against Activation in Quiescent Muscle Stem Cells
D. Blackburn, K. Sahinyan, A. Hernnandez Corchado…·V. D. Soleimani
This study identifies the PAX7/NEDD4L axis as a checkpoint regulating quiescence in muscle stem cells, showing that Nedd4L deletion impairs quiescence and promotes activation.
DOI 10.1101/2023.05.10.540205