Author

V. Doffini

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 2 Assay:ATAC-seq· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Assay:spatial transcriptomics· 1 Approach:statistical model· 1 Research Focus:trajectory inference· 1

Frequent Co-Authors

M. Nash· 2 shared A. A. Schoepfer· 1 shared C. Kueng· 1 shared H. Liu· 1 shared J. Ren· 1 shared R. Vanella· 1 shared Z. Liu· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

7 top collaborators · 13 mutual co-author links

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2 shared papersBiophysics

M. Nash

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Iterative Machine Learning for Classification and Discovery of Single-molecule Unfolding Trajectories from Force Spectroscopy Data

V. Doffini, H. Liu, Z. Liu, M. Nash

This paper introduces FUSION, a machine learning workflow for classifying and discovering protein unfolding trajectories from force spectroscopy data, achieving high accuracy and identifying new unfolding pathways.

bioRxiv · Aug 8, 2023Biophysics

Understanding Activity-Stability Tradeoffs in Biocatalysts by Enzyme Proximity Sequencing

R. Vanella, C. Kueng, A. A. Schoepfer, V. Doffini, J. Ren, M. Nash

The paper introduces EP-Seq, a method to simultaneously measure enzyme stability and activity across thousands of mutations, and applies it to D-amino acid oxidase to identify activity-stability tradeoffs.

bioRxiv · Feb 24, 2023Bioengineering