Author

V. Encheva

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Microbiology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 3 Research Focus:host-pathogen & immune response· 2 Research Focus:cell type annotation· 1 Research Focus:metabolism & bioenergetics· 1 Assay:metabolomics· 1 Organism:plant (other)· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

A. P. Snijders· 3 shared B. Clough· 2 shared D. Fisch· 2 shared A. A. Holder· 1 shared A. Prommaban· 1 shared A. Shenoy· 1 shared A. Snijders· 1 shared A. Theisen· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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3 shared papersMicrobiology

A. P. Snijders

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

p97/VCP targets Toxoplasma gondii vacuoles for parasite restriction in interferon-stimulated human cells

B. Clough, D. Fisch, T. H. Mize, V. Encheva, A. Snijders, E. Frickel

This study identifies p97/VCP as an IFN-gamma-dependent host factor that restricts Toxoplasma gondii by acidifying the parasitophorous vacuole in multiple human cell types.

bioRxiv · Jun 20, 2023 · PreprintImmunology

Metabolic turnover and dynamics of modified ribonucleosides by 13C labeling

P. A. Gameiro, V. Encheva, M. Silva dos Santos, J. I. MacRae, J. Ule

This study introduces 13C-dynamods to quantify the turnover of modified ribonucleosides in RNA, revealing distinct kinetic behaviors of m6A and m7G and their responses to stress conditions.

bioRxiv · Jul 20, 2021Biochemistry

Human GBP1 differentially targets Salmonella and Toxoplasma to license recognition of microbial ligands and caspase-mediateddeath

D. Fisch, B. Clough, M.-C. Domart, V. Encheva, H. Bando, A. P. Snijders, L. M. Collinson, M. Yamamoto, A. Shenoy, E.-M. Frickel

This study identifies GBP1's differential targeting of Salmonella and Toxoplasma to regulate caspase-mediated cell death and microbial ligand recognition.

bioRxiv · Apr 23, 2020Microbiology

Protein ubiquitylation is essential for the schizont to merozoite transition in Plasmodium falciparum blood-stage development

Y. Wu, V. Encheva, J. L. Green, E. Lasonder, A. Prommaban, S. Kunzelmann, E. Christodoulou, M. Grainger, N. Truongvan, S. Bothe, V. Sharma, W. Song, I. Pinzuti, C. Uthaipibull, S. Srichairatanakool, , A. A. Holder

This paper identifies ubiquitylation sites in Plasmodium falciparum and shows that ubiquitylation is essential for the schizont to merozoite transition.

bioRxiv · Sep 4, 2019 · PreprintMicrobiology

Functional cross-talk between allosteric effects of activating and inhibiting ligands underlies PKM2 regulation

J. A. Macpherson, A. Theisen, L. Masino, L. Fets, P. C. Driscoll, V. Encheva, A. P. Snijders, S. R. Martin, J. Kleinjung, P. E. Barran, F. Fraternali, D. Anastasiou

The paper investigates how PKM2 activity is regulated by simultaneous binding of activating and inhibiting ligands, revealing a mechanism for integrating allosteric inputs.

bioRxiv · Jul 26, 2018Biochemistry