Author

S. Kunzelmann

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Microbiology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:cell signaling & trafficking· 4 Assay:proteomics· 4 Research Focus:cell type annotation· 2 Research Focus:development & morphogenesis· 2 Organism:human· 2 Organism:mouse· 2 Approach:biophysical modeling· 1

Frequent Co-Authors

B. Stieglitz· 2 shared E. Christodoulou· 2 shared I. Pinzuti· 2 shared W. Song· 2 shared A. A. Holder· 1 shared A. Fornili· 1 shared A. P. Snijders· 1 shared A. Pandini· 1 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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2 shared papersBiochemistry

B. Stieglitz

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Activation loop phosphorylation and cGMP saturation of PKG regulate egress of malaria parasites.

K. Koussis, S. Haase, C. Withers-Martinez, H. R. Flynn, S. Kunzelmann, E. Christodoulou, F. Ibrahim, M. Skehel, D. A. Baker, M. J. Blackman

This study shows that PKG regulation in malaria parasites involves cGMP saturation and activation loop phosphorylation, with phosphorylation being essential for in vivo function.

bioRxiv · Feb 4, 2024Microbiology

WNK1-dependent water influx is required for CD4+ T cell activation and T cell-dependent antibody responses

J. Biggs O'May, L. Vanes, L. de Boer, H. Hartweger, S. Kunzelmann, D. Hayward, M. Llorian, D. A. Lewis, R. Koechl, V. Tybulewicz

This study shows that WNK1-dependent water influx is essential for CD4+ T cell proliferation and T cell-dependent antibody responses.

bioRxiv · Mar 16, 2022Immunology

N4BP1 is dimerization-dependent linear ubiquitin reader regulating TNFR1 signalling through linear ubiquitin binding and Caspase-8-mediated processing

K. W. Kliza, W. Song, I. Pinzuti, S. Schaubeck, S. Kunzelmann, D. Kuntin, A. Fornili, A. Pandini, K. Hofmann, J. Garnett, B. Stieglitz, K. Husnjak

This study identifies N4BP1 as a dimerization-dependent linear ubiquitin reader that regulates TNFR1 signaling by modulating NF-κB and apoptosis pathways.

bioRxiv · Nov 2, 2021 · PreprintBiochemistry

The speed of GTP hydrolysis determines GTP cap size and controls microtubule stability

J. Roostalu, C. Thomas, N. I. Cade, S. Kunzelmann, I. A. Taylor, T. Surrey

This study shows that GTP hydrolysis speed affects GTP cap size and microtubule stability by influencing EB protein binding and regulatory hub formation.

bioRxiv · Sep 23, 2019Biochemistry

Protein ubiquitylation is essential for the schizont to merozoite transition in Plasmodium falciparum blood-stage development

Y. Wu, V. Encheva, J. L. Green, E. Lasonder, A. Prommaban, S. Kunzelmann, E. Christodoulou, M. Grainger, N. Truongvan, S. Bothe, V. Sharma, W. Song, I. Pinzuti, C. Uthaipibull, S. Srichairatanakool, , A. A. Holder

This paper identifies ubiquitylation sites in Plasmodium falciparum and shows that ubiquitylation is essential for the schizont to merozoite transition.

bioRxiv · Sep 4, 2019 · PreprintMicrobiology