Redundant cytokine requirement for intestinal microbiota-induced Th17 cell differentiation in draining lymph nodes
T. Sano, T. Kageyama, V. Fang, R. Kedmi, J. Talbot, A. Chen, R. Kurakake, Y. Yang, C. Ng, S. R. Schwab, D. R. Littman
This study identifies redundant cytokine signals, particularly IL-6, IL-21, and IL-23, that drive Th17 cell differentiation in mesenteric lymph nodes induced by segmented filamentous bacteria.
bioRxiv · Apr 21, 2020Immunology