BiochemistrybioRxiv
A Crystallographic Snapshot of SARS-CoV-2 Main Protease Maturation Process
G. Noske, A. Nakamura, V. Gawriljuk…·A. S. de Godoy
This paper presents a crystal structure of an immature SARS-CoV-2 main protease, revealing conformational changes that hinder dimerization and activity, and identifies potential therapeutic targets.
DOI 10.1016/j.jmb.2021.167118