Author

G. Lima

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biochemistry· 1 Immunology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Research Focus:benchmarking· 2 Research Focus:drug response / drug discovery· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 1 Organism:non-human primate· 1 Research Focus:phylogenetics / evolution· 1 Assay:protein structure· 1

Frequent Co-Authors

B. Smith· 2 shared K. W. Witwer· 2 shared L. Jiang· 2 shared M. R. Richardson· 2 shared O. Gololobova· 2 shared T. Driedonks· 2 shared V. Mahairaki· 2 shared A. Nakamura· 1 shared

Activity by Year

2020-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersPharmacology & Toxicology

B. Smith

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Pharmacokinetics and biodistribution of extracellular vesicles administered intravenously and intranasally to Macaca nemestrina

T. Driedonks, L. Jiang, B. Carlson, Z. Han, G. Liu, S. E. Queen, E. N. Shirk, O. Gololobova, L. H. Nyberg, G. Lima, L. Paniushkina, M. Garcia-Contreras, K. Schonvisky, M. Stover, S. Guerrero-Martin, , K. W. Witwer

This study investigates the pharmacokinetics and biodistribution of extracellular vesicles in macaques via intravenous and intranasal routes, finding longer plasma circulation times and organ uptake with IV administration, but limited systemic distribution with IN.

bioRxiv · Jul 28, 2021Pharmacology & Toxicology

A bacterial extracellular vesicle-based intranasal vaccine against SARS-CoV-2 protects against disease and elicits neutralizing antibodies to wild-type virus and Delta variant

L. Jiang, T. Driedonks, M. Lowman, W. S. Jong, H. B. van den Berg van Saparoea, S. Dhakal, R. Zhou, C. Caputo, K. Littlefield, I. Sitaras, M. W. Chen, G. Lima, O. Gololobova, B. Smith, V. Mahairaki, , K. W. Witwer

bioRxiv · Jun 28, 2021Immunology

A Crystallographic Snapshot of SARS-CoV-2 Main Protease Maturation Process

G. Noske, A. Nakamura, V. Gawriljuk, R. Fernandes, G. Lima, H. Rosa, H. Pereira, A. Zeri, A. Nascimento, M. Freire, G. Oliva, A. S. de Godoy

This paper presents a crystal structure of an immature SARS-CoV-2 main protease, revealing conformational changes that hinder dimerization and activity, and identifies potential therapeutic targets.

bioRxiv · Dec 23, 2020Biochemistry