Author

V. Introini

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Biophysics· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 3 Organism:human· 3 Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

J. C. Rayner· 2 shared P. Cicuta· 2 shared A. B. Ward· 1 shared A. L. Smith· 1 shared A. Marin-Menendez· 1 shared B. Greenhouse· 1 shared B. S. Penman· 1 shared C. B. Bau· 1 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersMicrobiology

J. C. Rayner

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Broadly inhibitory antibodies against severe malaria virulence proteins

R. A. Reyes, S. S. R. Raghavan, N. K. Hurlburt, V. Introini, I. H. Kana, R. W. Jensen, E. Martinez-Scholze, M. Gestal-Mato, C. B. Bau, M. L. Fernandez-Quintero, J. R. Loeffler, J. A. Ferguson, W.-H. Lee, G. M. Martin, T. G. Theander, , T. Lavstsen

The paper identifies two human monoclonal antibodies that broadly inhibit PfEMP1's binding to EPCR, a key process in severe malaria pathogenesis.

bioRxiv · Jan 25, 2024Immunology

The structure of a Plasmodium vivax Tryptophan Rich Antigen suggests a lipid binding function for a pan-Plasmodium multi-gene family

P. Kundu, D. Naskar, S. McKie, S. Dass, U. Kanjee, V. Introini, M. U. Ferreira, M. Duraisingh, J. E. Deane, J. C. Rayner

The paper determines the structure of a Plasmodium vivax TRAg and shows it binds lipids, suggesting a role in membrane remodeling during red blood cell invasion.

bioRxiv · Sep 30, 2022Microbiology

The erythrocyte membrane properties of beta thalassaemia heterozygotes and their consequences for Plasmodium falciparum invasion

V. Introini, A. Marin-Menendez, G. Nettesheim, Y.-C. Lin, S. N. Kariuki, A. L. Smith, L. Jean, J. N. Brewin, D. C. Rees, P. Cicuta, J. C. Rayner, B. S. Penman

This study examines beta thalassaemia heterozygous erythrocytes' properties and their effect on Plasmodium falciparum invasion, finding no overall reduction in invasion efficiency.

bioRxiv · Jan 13, 2022Microbiology

Centripetal nuclear shape fluctuations associate with chromatin condensation towards mitosis

V. Introini, G. R. Kidiyoor, G. Porcella, M. Foiani, P. Cicuta, M. Cosentino Lagomarsino

The paper examines nuclear shape fluctuations during the cell cycle and finds they correlate with chromatin condensation and nuclear-envelope breakdown in mitosis.

bioRxiv · Nov 25, 2021 · PreprintBiophysics