D. C. Rees

Postdoctoral Scholar Recruitment and Hiring Practices in STEM: A Pilot Study

This study examines postdoctoral hiring practices in STEM, finding that the process is decentralized and opaque, with faculty making individual decisions, which complicates efforts to ensure equitable hiring.

Modeling the Correlation between Z and B in an X-ray Crystal Structure Refinement

The paper models the relationship between Z and B factors in X-ray crystal structure refinement for sulfur in a [4Fe:4S] cluster, showing similar fractional changes and implications for distinguishing atom types.

Anaerobic single particle cryoEM of nitrogenase

This study presents anaerobic single particle cryoEM structures of nitrogenase from Azotobacter vinelandii, revealing structural dynamics and potential asymmetric binding.

Selenocyanate Derived Se-Incorporation into the Nitrogenase Fe Protein Cluster

This study reports crystallographic evidence of ATP-dependent chalcogenide exchange at the Fe4S4 cluster of the nitrogenase Fe protein using potassium selenocyanate as a selenium source.

The erythrocyte membrane properties of beta thalassaemia heterozygotes and their consequences for Plasmodium falciparum invasion

This study examines beta thalassaemia heterozygous erythrocytes' properties and their effect on Plasmodium falciparum invasion, finding no overall reduction in invasion efficiency.

Glutathione binding to the plant At Atm3 transporter and implications for the conformational coupling of ABC transporters

The paper determines structures of AtAtm3 in multiple conformational states and examines glutathione binding and its implications for ABC transporter function.

Fluorescence Activation Mechanism and Imaging of Drug Permeation with New Sensors for Smoking-Cessation Ligands

The paper develops new fluorescent sensors to study the pharmacokinetics of nicotinic partial agonists in living cells and identifies differences in membrane crossing rates among these drugs.

Characterization of the ABC methionine transporter from Neisseria meningitidis reveals that MetQ is a lipoprotein

The paper characterizes NmMetQ, showing it is a lipoprotein that binds methionine analogs and activates its cognate ABC transporter, challenging the conventional localization of SBPs in Gram-negative bacteria.

Crosslinking of nucleotide binding domains improves the coupling efficiency of an ABC transporter

This study shows that disulfide crosslinking of NaAtm1 improves ATP hydrolysis coupling to GSSG transport, suggesting enhanced conformational dynamics may cause inefficient ATP use in ABC transporters.