Author

V. Izzi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cancer & tumor microenvironment· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1

Frequent Co-Authors

A. Caravella· 1 shared A. Lauria· 1 shared F. Warnberg· 1 shared G. Azzato· 1 shared G. De Marco· 1 shared G. Forte· 1 shared G. Martinez-Nieto· 1 shared G. Rask· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

A. Caravella

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Mycolic acid and cholesterol induced transcriptomic adaptations in wild type and Mce complex ATPase subunit deleted strain of M. tuberculosis H37Rv

M. A. Rahman, V. Izzi, L. W. Riley, R. Venkatesan

This study compares transcriptomic responses of wild type and mkl-deleted M. tuberculosis strains to cholesterol and mycolic acid, revealing differential gene expression patterns and insights into adaptation strategies.

bioRxiv · May 13, 2024 · PreprintBiochemistry

TGF-β induces matrisome pathological alterations and EMT in patient-derived prostate cancer tumoroids

S. Fernandes, J. Oliver-De La Cruz, M. Cassani, S. Morazzo, H. Durikova, A. Caravella, P. Fiore, G. Azzato, G. De Marco, A. Lauria, V. Izzi, V. Bosakova, J. Fric, P. Filipensky, G. Forte

This study shows TGF-β signaling drives ECM changes and EMT in prostate cancer tumoroids, promoting tumor progression.

bioRxiv · Apr 3, 2023Cancer Biology

Collagen XVIII promotes breast cancer through EGFR/ErbB signaling and its ablation improves the efficacy of ErbB-targeting inhibitors

R. Devarajan, H. Peltoketo, V. Izzi, H. J. Ruotsalainen, S. Kauppila, M.-R. Vaisanen, G. Rask, G. Martinez-Nieto, S.-M. Karppinen, T. Vaisanen, I. Kaur, J. P. Koivunen, T. Sasaki, R. Winqvist, F. Warnberg, , R. Heljasvaara

This study shows that collagen XVIII promotes breast cancer via EGFR/ErbB signaling and sustains cancer stem cells, and its inhibition enhances the effectiveness of ErbB-targeting therapies.

bioRxiv · Jan 10, 2022 · PreprintCancer Biology