Multimodal delineation of a layer of effector function among exhausted CD8 T cells in tumors
A. Ray, M. Bassette, K. H. Hu, L. F. Pass, B. Samad, A. Combes, V. Johri, B. Davidson, G. Hernandez, I. Zaleta-Linares, M. F. Krummel
The paper identifies a potent effector state among exhausted CD8 T cells in tumors using multimodal CITE-Seq, showing enhanced cytokine production and tumor-killing ability.
bioRxiv · Sep 26, 2023Immunology